IVF-C is a preparation of human chorionic gonadotropin (hCG) extracted and purified from the urine of pregnant women. hCG is a water-soluble polypeptide hormone produced by the human placenta.
The action of hCG is virtually identical to that of pituitary LH, although hCG also seems to have a small degree of FSH activity. In male, IVF-C is given in an attempt to stimulate the interstitial cells of the testes (cells of Leydig) to produce androgen and in female, in the second phase of the cycle, to maintain the functional integrity of the corpus luteum and to stimulate its secretion of progesterone.
In ART, IVF-C should be administered for the final development and maturation of the ovarian follicles and to trigger ovulation. Therefore, IVF-C must be given following the administration of Urofollitropin, Menotropin or rFSH.
Appearance of powder: white to off-white lyophilisation cake
Appearance of solvent: clear colourless solution